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Infectious Diseases in Obstetrics and Gynecology
Volume 7 (1999), Issue 5, Pages 227-229

Semiquantitative Bacterial Observations With Group B Streptococcal Vulvovaginitis

Creighton University School of Medicine, 2500 California Plaza, Omaha 68178, NE, USA

Received 8 January 1999; Accepted 21 June 1999

Copyright © 1999 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective: Group B streptococcal (GBS) vulvovaginitis is a poorly-delineated clinical entity. The purpose of this study is to report semiquantitative data from four cases of GBS vulvovaginitis and to comment on their significance in terms of the in vitro inhibitory capabilities of GBS.

Methodology: Four patients whose clinical presentations were consistent with GBS vulvovaginitis, from whom GBS was isolated and for whom semi-quantitative as well as qualitative microbiologic data existed, were identified.

Results: To produce vulvovaginitis, GBS must be at a high multiplicity (108 CFU/g of vaginal fluid). Single coisolates were identified in three of the four cases (two cases of Escherichia coli and one case of Staphylococcus aureus). Group B streptococcus does not inhibit either of these bacteria in vitro.

Conclusion: When the growth requirements for the demonstration of in vitro inhibition for GBS or lack thereof are met in vivo, the in vivo observations are consistent with those projected from the in vitro data. Infect. Dis. Obstet. Gynecol. 7:227–229, 1999.