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Infectious Diseases in Obstetrics and Gynecology
Volume 12, Issue 1, Pages 13-16

Cytolytic Vaginosis: Misdiagnosed as Candidal Vaginitis

1Department of Microbiology, Marmara University School of Medicine, Turkey
2Gynecology and Obstetrics Department, Hacettepe University Hospital, Turkey

Received 15 August 2003; Accepted 14 November 2003

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives: In this study, 210 women with vaginal discharge and other symptoms/signs of genital pathology suggestive of vulvovaginal candidiasis (VVC) were involved in order to distinguish true VVC and cytolytic vaginosis (CV) cases.

Methods: Fungal cultures, 10% potassium hydroxide (KOH) and Gram stained preparations and pH measurements were performed on the vaginal discharge material of each patient.

Results: Fifteen patients (7.1%) were diagnosed with cytolytic vaginosis according to their clinical and microbiological findings, including abundant lactobacilli, fragmented epithelial cells and/or free nuclei due to cytolysis, seen in their discharge materials on microscopic examination, but no fungal growth.

Conclusions: The results of this study may contribute to the reports in the literature indicating the importance of such disorders, which are generally misdiagnosed as candidiasis.