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Infectious Diseases in Obstetrics and Gynecology
Volume 13 (2005), Issue 2, Pages 63-67

Detection of Candida Species in Vaginal Samples in a Clinical Laboratory Setting

1Medical Diagnostic Laboratories, L.L.C., 2439 Kuser Road, Hamilton, NJ 08690, USA
2The Women’s Center for Continence, Marlton, NJ, USA

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To present the detection rates of Candida species in vaginal samples from patients visiting physicians.

Methods. The presence of C. albicans, C. glabrata, C. parapsilosis and C. tropicalis in 3978 vaginal swabs from patients in six US states was detected by PCR amplification.

Results. Candida DNA was detected in 33.1% of the population studied. Of the 1316 positive samples, 80.2% contained C. albicans, 14.3% contained C. glabrata, 5.9% contained C. parapsilosis and 8.0% contained C. tropicalis. Comparing samples by patients' state of residence revealed an association with the detection of C. glabrata (p =0.029). Comparing samples by patients' age revealed a decrease in the overall detection of Candida (p < 0.001) and C. albicans (p < 0.001), concomitant with an increase in the detection of C. glabrata (p < 0.001) and C. parapsilosis (p = 0.025).

Conclusions. These results provide geographic- and age-specific data on four Candida species associated with vaginitis.