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Infectious Diseases in Obstetrics and Gynecology
Volume 2006, Article ID 13890, 3 pages
Clinical Study

Does Rubella Immunity Predict Measles Immunity? A Serosurvey of Pregnant Women

1Department of Obstetrics and Gynecology, Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
2Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30322, USA

Received 17 January 2006; Revised 11 May 2006; Accepted 5 June 2006

Copyright © 2006 Colleen M. Kennedy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. This study was undertaken to determine whether rubella immunity infers measles immunity in pregnant women. Methods. Stored serum samples were obtained from the Iowa State Hygienic Laboratory for evaluation of rubella and measles immunities with IgG enzyme-linked immunosorbent assay. Results. Nine hundred serum samples were obtained for testing. The average age of the women at the time of antepartum serum collection was 28 (range, 14 to 44) years. Measles and rubella immunity were 88% and 98%, respectively; there was no effect of immunity status by age identified. Eighty eight percent of those with rubella immunity were also measles immune. There was no association between paired rubella and measles immunity identified, P<.0001. Discussion. Known rubella immunity did not infer measles immunity in our population. Thus, we recommend that pregnant women exposed to measles be tested and appropriately treated if they are found to be nonimmune.