Our objective is to investigate the relationship between drug and
menstrual cycle symptoms in HIV+ women receiving antiretroviral
therapy (HAART). Interviews were done for 12 weeks with 54 HIV+
women receiving HAART. Patients were asked if they experienced
any of 28 symptoms associated with HAART and the menstrual cycle
and about HAART adherence. Weeks were divided into menstrual weeks
(MWs), premenstrual weeks (PWs), and other weeks. Women reported
more bloating (
J G Bartlett, “Pocket Guide to Adult HIV/AIDS Treatment,” January 2005. Found at http://hopkins-aids.edu/publications/pocketguide/pocketgd0105.pdf. Last accessed February 16, 2005.
View at: Google Scholar“Guidelines for the Use of Antiretroviral Agents in HIV-Infected Adults and Adolescents,” http://hivatis.org, 2004. Last accessed February 16, 2005.
View at: Google ScholarD L Paterson, S Swindells, J Mohr et al., “Adherence to protease inhibitor therapy and outcomes in patients with HIV infection,” Annals of Internal Medicine, vol. 133, no. 1, pp. 21–30, 2000.
View at: Google ScholarP Tsasis, “Adherence assessment to highly active antiretroviral therapy,” AIDS Patient Care and STDs, vol. 15, no. 3, pp. 109–115, 2001.
View at: Google ScholarS A Safren, M W Otto, J L Worth et al., “Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring,” Behaviour Research and Therapy, vol. 39, no. 10, pp. 1151–1162, 2001.
View at: Google ScholarA Molassiotis, V Nahas-Lopez, W YR Chung, S WC Lam, C KP Li, and T FJ Lau, “Factors associated with adherence to antiretroviral medication in HIV-infected patients,” International Journal of STD & AIDS, vol. 13, no. 5, pp. 301–310, 2002.
View at: Google ScholarA Ammassari, R Murri, P Pezzotti et al., “Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection,” JAIDS: Journal of Acquired Immune Deficiency Syndromes, vol. 28, no. 5, pp. 445–449, 2001.
View at: Google ScholarA A Monforte, A C Lepri, G Rezza et al., “Insights into the reasons for discontinuation of the first highly active antiretroviral therapy (HAART) regimen in a cohort of antiretroviral naive patients,” AIDS, vol. 14, no. 5, pp. 499–507, 2000.
View at: Google ScholarL M Kuyper, E Wood, J SG Montaner, B Yip, J M O'Connell, and R S Hogg, “Gender differences in HIV-1 RNA rebound attributed to incomplete antiretroviral adherence among HIV-infected patients in a population-based cohort,” JAIDS: Journal of Acquired Immune Deficiency Syndromes, vol. 37, no. 4, pp. 1470–1476, 2004.
View at: Google ScholarK J Roberts, “Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens,” AIDS Patient Care and STDs, vol. 14, no. 3, pp. 155–168, 2000.
View at: Google ScholarS Cu-Uvin, D J Wright, D Anderson et al., “Hormonal levels among HIV-1-seropositive women compared with high-risk HIV-seronegative women during the menstrual cycle,” Journal of Women's Health & Gender-Based Medicine, vol. 9, no. 8, pp. 857–863, 2000.
View at: Google ScholarR L Robinson and R W Swindle, “Premenstrual symptom severity: impact on social functioning and treatment-seeking behaviors,” Journal of Women's Health & Gender-Based Medicine, vol. 9, no. 7, pp. 757–768, 2000.
View at: Google ScholarR H Moos, Menstrual Distress Questionnaire Manual, Western Psychological Services, Los Angeles, Calif, 1991.