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Infectious Diseases in Obstetrics and Gynecology
Volume 2006 (2006), Article ID 57492, 4 pages
Clinical Study

Patterns of Antibiotic Resistance Among Group B Streptococcus Isolates: 2001–2004

Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Medical School at Houston, Houston, TX 77030, USA

Received 15 December 2004; Revised 30 June 2005; Accepted 31 July 2005

Copyright © 2006 Lubna Chohan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The objectives were to determine the prevalence of group B streptococcus (GBS) and to characterize antibiotic resistance patterns. All pregnant women presenting to the triage units at two urban hospitals during three intervals from 2001 to 2004 were included. Each interval lasted approximately four weeks. Swabs were inoculated into selective broth and cultured on tryptic soy agar with 5% sheep blood. GBS was identified using the StrepTex latex agglutination system. GBS positive cultures were tested for their resistance to ampicillin, erythromycin, clindamycin, and cefazolin. GBS was isolated from 154 (12.2%) of 1264 swabs collected during the study period. African-American women were more likely to be colonized with GBS than Caucasians and Hispanics. Resistance to routinely administered antibiotics was common, but there were no statistically significant increases in resistance to antibiotics over the study period. Ongoing surveillance of antibiotic resistance patterns is important in determining optimal prophylaxis and therapy.