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Infectious Diseases in Obstetrics and Gynecology
Volume 2006, Article ID 79512, 5 pages
Clinical Study

Postpartum Morbidity Associated With Advanced HIV Disease

1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University, Detroit 48201, MI, USA
2Department of Internal Medicine, Division of Infectious Diseases, Wayne State University, Detroit 48201, MI, USA

Received 28 May 2006; Revised 25 September 2006; Accepted 10 October 2006

Copyright © 2006 Judette Louis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To investigate the postpartum morbidity and postpartum management of febrile morbidity associated with advanced HIV infection. Methods. A case control study of HIV infected women at a tertiary care center during January 2000–June 2005 was performed. Postpartum morbidity was defined as endometritis, blood transfusion, wound complication, readmission, infectious morbidity, or unexpected surgery. Results. Women in Group 1 had AIDS (N=33), Group 2 were relatively immunocompetent HIV infected women (N=115), and Group 3 were uninfected women (N=152). Group 1 was more likely to have a postpartum morbidity (32.3 versus 19.3 and 13.2%, P=.03) and to have postpartum imaging 18.8 versus 7.9 and 2.6%, P=.002. After controlling for potential confounders, cesarean delivery (OR 6.2, 95% CI 2.1–505.5) but not advanced HIV disease was associated with an increased risk of postpartum morbidity. Conclusion. Cesarean delivery and not advanced HIV disease increases the risk of postpartum morbidity in women with AIDS.