Infectious Diseases in Obstetrics and Gynecology / 2009 / Article / Tab 3

Clinical Study

Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital Herpes

Table 3

Post-hoc Analysis of Patients with Documented Incident Infection—Results from the First Treatment Period.

HSV-2 AntibodyHSV-2 Antibody
Negativea Positive

Percent days with total shedding, Mean (SD %)   -valueb43.8 (18.6 )11.2 (14.8)

Percent days with subclinical shedding, Mean (SD %)   -valueb31.9 (12.8 )8.9 (14.1)

Proportion of subjects recurrence-freec, (%)0 (0)19 (61)

aThis group includes 3 subjects who were HSV-1 and HSV-2 seronegative, and one subject who was HSV-1 seropositive and HSV-2 seronegative. bThis was an exploratory analysis; -values should be regarded only as a rough guide to the magnitude of differences between groups. cThis difference was statistically significant ( ); however, this was an exploratory analysis.

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