Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial Vaginosis

Table 2

Odds ratio for having detectable HIV-1 in cervicovaginal lavage when individual bacteria are detected by PCR.

Bacterial species	𝑁 (%)^a	OR	95% CI	𝑃 value
(any versus none)
Lactobacillus spp.	60 (94%)	N/A^b	–-	–-
Lactobacillus crispatus	23 (37%)	3.17	0.85, 11.8	.09
Gardnerella vaginalis	54 (84%)	17.2	0.48, 619	.12
Leptotrichia/Sneathia	38 (59%)	0.61	0.17, 2.13	.44
Megasphaera spp.	20 (31%)	0.91	0.26, 3.17	.88
BVAB1	12 (19%)	3.07	0.68, 14.0	.15
BVAB2	26 (41%)	2.59	0.74, 9.0	.14
BVAB3	17 (27%)	3.03	0.63, 14.7	.17

^aNumber of women with bacteria detected by qPCR. ^bCannot be computed, because only 4 women had no lactobacilli, and all had detectable cervicovaginal HIV shedding (OR would be infinity).