Clinical Study

Kinetics and Determining Factors of the Virologic Response to Antiretrovirals during Pregnancy

Table 1

Demographics and baseline characteristics of HIV infection.

Characteristic or Median (% or IQR)

Patients105
 One pregnancy with CHIP93 (89)
 Two pregnancies with CHIP12 (11)
Maternal age at delivery30 (26, 34)
Race
 White72 (68.6)
 Black31 (29.5)
 Other2 (1.9)
Ethnicity
 Hispanic41 (39)
 Not Hispanic64 (61)
Country of origin
 African countr 15 (14)
 Mexico17 (16)
 USA66 (63)
 Other4 (4)
 Unknown3 (3)
HIV risk factor
 IV drug use12 (11)
 Heterosexual sex97 (92)
 Transfusion5 (5)
HIV diagnosis
 Prior to first pregnancy at CHIP70 (67)
 During pregnancy35 (33)
ARV experience
 Naive51 (44)
 Experienced on therapy at the onset of pregnancy29 (25)
 Experienced off therapy at the onset of pregnancy30 (26)
 Unknown7 (5)
Plasma HIV RNA at first visit109 pregnancies
 Median (range)2657 (225, 16700)
400 copies/mL78 (72)
CD4+ count at first visit108 pregnancies
 Median (range)450 (269, 628)
200 cells/ 13 (12%)

Includes Ethiopia, Liberia, Nigeria, Kenya, and Somalia.
Nine patients have more than one risk factor.