Research Article

Pretreatment with Pancaspase Inhibitor (Z-VAD-FMK) Delays but Does Not Prevent Intraperitoneal Heat-Killed Group B Streptococcus-Induced Preterm Delivery in a Pregnant Mouse Model

Figure 5

Intrauterine HK-GBS injection induces placental m-calpain expression in a time-dependent manner. Day 14.5 pregnant mice were euthanized 14 hours after exposure to PBS (i) or HK-GBS (ii). Placentas were removed and stained for m-calpain. Data from a representative of three separate experiments is shown.
749432.fig.005a
(a) PBS
749432.fig.005b
(b) HK-GBS