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Infectious Diseases in Obstetrics and Gynecology
Volume 2011, Article ID 420905, 8 pages
Research Article

Chlamydia trachomatis Immune Evasion via Downregulation of MHC Class I Surface Expression Involves Direct and Indirect Mechanisms

1Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Science Center, New Orleans, LA 70112, USA
2Department of Obstetrics, Gynecology and Women's Health, University of Missouri School of Medicine, Columbia, MO 65202, USA

Received 31 December 2010; Accepted 15 February 2011

Academic Editor: Charlene Dezzutti

Copyright © 2011 Joyce A. Ibana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [13 citations]

The following is the list of published articles that have cited the current article.

  • Joyce Altamarino Ibana, Ashok Aiyar, Alison Jane Quayle, and Danny Joseph Schust, “Modulation of MICA on the surface of Chlamydia trachomatis-infected endocervical epithelial cells promotes NK cell-mediated killing,” FEMS Immunology and Medical Microbiology, vol. 65, no. 1, pp. 32–42, 2012. View at Publisher · View at Google Scholar
  • Paula Barrionuevo, M. Victoria Delpino, Roberto G. Pozner, Lis N. Velásquez, Juliana Cassataro, and Guillermo H. Giambartolomei, “ Brucella abortus induces intracellular retention of MHC-I molecules in human macrophages down-modulating cytotoxic CD8 + T cell responses ,” Cellular Microbiology, vol. 15, no. 4, pp. 487–502, 2012. View at Publisher · View at Google Scholar
  • Louise M. Hafner, David P. Wilson, and Peter Timms, “Development status and future prospects for a vaccine against Chlamydia trachomatis infection,” Vaccine, 2013. View at Publisher · View at Google Scholar
  • Lyndsey R. Buckner, Maria E. Lewis, Sheila J. Greene, Timothy P. Foster, and Alison J. Quayle, “Chlamydia trachomatis infection results in a modest pro-inflammatory cytokine response and a decrease in T cell chemokine secretion in human polarized endocervical epithelial cells,” Cytokine, 2013. View at Publisher · View at Google Scholar
  • Dorothee Fiegl, Danny Kaegebein, Elisabeth M. Liebler-Tenorio, Tanja Weisser, Mareen Sens, Melanie Gutjahr, and Michael R. Knittler, “Amphisomal Route of MHC Class I Cross-Presentation in Bacteria-Infected Dendritic Cells,” Journal Of Immunology, vol. 190, no. 6, pp. 2791–2806, 2013. View at Publisher · View at Google Scholar
  • Sam Vasilevsky, Gilbert Greub, and Denise Nardelli-Haefliger, “Genital Chlamydia trachomatis: Understanding the Roles of Innate and Adapti ve Immunity in Vaccine Research,” Clinical Microbiology Reviews, vol. 27, no. 2, pp. 346–370, 2014. View at Publisher · View at Google Scholar
  • Danny Kaegebein, Melanie Gutjahr, Christina Grosse, Annette B. Vogel, Juergen Roedel, and Michael R. Knittler, “Chlamydia trachomatis-Infected Epithelial Cells and Fibroblasts Retain the Ability To Express Surface-Presented Major Histocompatibility Complex Class I Molecules,” Infection and Immunity, vol. 82, no. 3, pp. 993–1006, 2014. View at Publisher · View at Google Scholar
  • Chrissy H. Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M. Harding-Esch, Sarah E. Burr, David C. W. Mabey, Robin L. Bailey, Matthew J. Burton, and Martin J. Holland, “Conjunctival Scarring in Trachoma Is Associated with the HLA-C Ligand of KIR and Is Exacerbated by Heterozygosity at KIR2DL2/KIR2DL3,” Plos Neglected Tropical Diseases, vol. 8, no. 3, 2014. View at Publisher · View at Google Scholar
  • Animesh Singh, and Sarah Karrar, “The Role of Intracellular Organisms in the Pathogenesis of Inflammatory Arthritis,” International Journal of Inflammation, vol. 2014, pp. 1–8, 2014. View at Publisher · View at Google Scholar
  • Stefanie Lagae, Annelien Dumont, and Daisy Vanrompay, “Examination of the in vivo immune response elicited by Chlamydia psittaci in chickens,” Veterinary Immunology and Immunopathology, 2015. View at Publisher · View at Google Scholar
  • Shardulendra P. Sherchand, Joyce A. Ibana, Arnold H. Zea, Alison J. Quayle, and Ashok Aiyar, “The high-risk human papillomavirus e6 oncogene exacerbates the negative effect of tryptophan starvation on the development of chlamydia trachomatis,” PLoS ONE, vol. 11, no. 9, 2016. View at Publisher · View at Google Scholar
  • Erik D. Cram, Ryan S. Simmons, Amy L. Palmer, William H. Hildebrand, Daniel D. Rockey, and Brian P. Dolan, “Enhanced Direct Major Histocompatibility Complex Class I Self-Antigen Presentation Induced by Chlamydia Infection,” Infection And Immunity, vol. 84, no. 2, pp. 480–490, 2016. View at Publisher · View at Google Scholar
  • Louise M Hafner, and Peter Timms, “Development of a Chlamydia trachomatis vaccine for urogenital infections: novel tools and new strategies point to bright future prospects,” Expert Review of Vaccines, vol. 17, no. 1, pp. 57–69, 2018. View at Publisher · View at Google Scholar