Research Article
Clinicopathological Comparison of Adenocarcinoma of Cervix and Endometrium Using Cell Cycle Markers: P16ink4a, P21waf1, and p27Kip1 on 132 Cancers
Table 5
Associations between P21waf1 expression and clinicopathologic parameter for adenocarcinoma of the cervix.
| | Characteristics | No. of patients | Positive, (%) () | Negative, (%) () | value |
| | Age (years) | | | | | | <35 | 3 | 2 (66.7) | 1(33.3) | 0.937 | | 35–54 | 22 | 15 (68.1) | 7 (31.8) | | ≥55 | 15 | 11 (73.3) | 4 (33.7) |
| | FIGO stage | | | | | | I-II | 30 | 23 (76.7) | 7 (23.3) | 0.111 | | III-IV | 10 | 5 (50.0) | 5 (50.0) |
| | Histology tumor differentiation | | | | | | Well/moderate | 25 | 16 (64.0) | 9 (36.0) | 0.285 | | Poor | 15 | 12 (80.0) | 3 (20.0) |
| | Infiltration depth | | | | | | Inner 2/3 | 13 | 10 (76.9) | 3 (23.1) | 0.507 | | Outer 1/3 or through | 27 | 18 (66.7) | 9 (33.3) |
| | Tumor length | | | | | | <20 mm | 11 | 7 (63.6) | 4 (36.4) | 0.589 | | >20 mm | 29 | 21 (72.4) | 8 (27.6) |
| | Tumor thickness | | | | | | <5 mm | 4 | 1 (25.0) | 3 (75.0) | 0.101 | | >5 mm | 36 | 27 (75.0) | 9 (25.0) |
| | Infiltration to corpus | | | | | | Yes | 17 | 9 (52.9) | 8 (47.1) | 0.043 | | No | 23 | 19 (82.6) | 4 (17.4) |
| | Vascular invasion | | | | | | Yes | 20 | 15 (75.0) | 5 (25.0) | 0.490 | | No | 20 | 13 (65.0) | 7 (35.0) |
| | Lymph node invasion | | | | | | Yes | 12 | 6 (50.0) | 6 (50.0) | 0.071 | | No | 28 | 22 (78.6) | 6 (21.4) |
| | Histologic type | | | | | | Endocervical | 25 | 17 (68.0) | 8 (32.0) | 0.722 | | Non endocervical | 15 | 11 (73.3) | 4 (26.7) |
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