Research Article
Clinicopathological Comparison of Adenocarcinoma of Cervix and Endometrium Using Cell Cycle Markers: P16ink4a, P21waf1, and p27Kip1 on 132 Cancers
Table 7
Associations between P16INK4a expression and clinicopathologic parameter for endometrial adenocarcinoma.
| | Characteristics | No. patients | Positive, (%) () | Negative, (%) () | value |
| | Age (years) | | | | | | <50 | 28 | 5 (17.9) | 23 (82.1) | 0.148 | | 50–60 | 35 | 7 ( 20.0) | 28 (80.0) | | >60 | 29 | 11 (38.0) | 18 (62.0) |
| | FIGO stage | | | | | | I | 50 | 12 (24.0) | 38 (76.0) | 0.809 | | II–IV | 42 | 11 (26.2) | 31 (73.8) |
| | Myometrial invasion | | | | | | < | 45 | 9 (20.0) | 36 (80.0) | 0.278 | | > | 47 | 14 (29.8) | 33 (70.2) |
| | Histologic grade | | | | | | G1-G2 | 62 | 11 (17.7) | 51 (82.2) | 0.014 | | G3 | 30 | 12 (40.0) | 18 (60.0) |
| | Postmenopausal status | | | | | | Yes | 54 | 16 (29.6) | 38 (70.4) | 0.222 | | No | 38 | 7 (18.4) | 31 (81.6) |
| | Histologic type | | | | | | Endometrioid | 75 | 16 (21.3) | 59 (78.7) | 0.888 | | Non endometrioid | 17 | 7 (41.2) | 10 (58.8) |
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