Infectious Diseases in Obstetrics and Gynecology / 2012 / Article / Tab 2

Research Article

Progress towards Elimination of HIV Mother-to-Child Transmission in the Dominican Republic from 1999 to 2011

Table 2

HIV mother-to-child transmission risk in the 1999–2008 and 2009–2011 periods, by prenatal antiretroviral, delivery route, and infant feeding prevention strategies, Dominican Republic.

All perinatally exposed142/1,274 (11.1%)12/302 (4.0%)*
 Any maternal antiretrovirals54/861 (6.3)10/267 (3.7)
  HAART1 all4/157 (2.5)5/174 (2.9)
   AZT + 3TC + NVP24/157 (2.5)0/59
   AZT + 3TC + Lopinavir/r3 5/115 (4.3)
  Non-HAART multidose 4/80 (5.0)
  AZT-containing regimen
  Single-dose NVP ALL32/506 (6.3)3/60 (5.0)
   8 hours precaesarean25/395 (6.3)0/2
   Labor onset5/78 (6.4)
   At delivery2/30 (6.7)
   Unspecified 3/58 (5.2)
  Unknown14/211 (11.6) 2/30 (6.7)
 None 88/413 (21.3) 2/35 (5.7)*

Delivery
 Vaginal68/285 (23.9)6/80 (7.5)*
 Caesarean60/882 (6.8) 5/199 (2.5)*
 Unknown14/107 (13.1)1/23 (4.3)*

Infant antiretrovirals
 Single-dose Nevirapine (SD NVP)48/782 (6.1)1/41 (2.4)
 SD-NVP after 72 hours1/13 (7.6)
 Zidovudine for six weeks7/139 (5.0)7/126 (5.6)
 Unknown/other/none32/340 (9.4)4/135 (3.0)

Infant feeding
 Breast fed only25/67 (37.3)0/2
 Mixed16/43 (37.2)0/4
 Formula only79/972 (8.1) 11/271 (4.1)*
 Unknown22/192 (11.5) 1/25 (4.0)*

* P < .05, comparison by time period, 1999–2008 versus 2009–2011.
P < .01 within period, by strategy.
1Highly active antiretroviral therapy.
2AZT-3TC-NVP: zidovudine, lamivudine, nevirapine.
3AZT-3TC-Lop/r: zidovudine, lamivudine, lopinavir (ritonavir boosted).

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