Infectious Diseases in Obstetrics and Gynecology / 2013 / Article / Tab 2

Clinical Study

Duration of Intrapartum Antibiotics for Group B Streptococcus on the Diagnosis of Clinical Neonatal Sepsis

Table 2

Effect of the duration of intrapartum antibiotic prophylaxis on the diagnosis of neonatal clinical sepsis.

Duration of IAPNumber of womenDiagnosis of neonatal clinical sepsis

<2 hours3856 (1.6)
2 to <4 hours7647 (0.9)
≥4 hours3,63315 (0.4)

RR (95% CI)#
Crude Adjusted P

<2 hour versus ≥4 hours3.8 (1.5–9.7).013.5 (1.3–9.6).02
2 to <4 hours versus ≥4hours2.2 (0.9–5.4).082.1 (0.8–5.5).12

IAP: intrapartum antibiotic prophylaxis; RR: relative risk; CI: 95th percentile confidence interval.
Data are (%) unless otherwise specified.
#In multivariate analysis, odds ratios (OR) were assumed to approximate relative risks (RR) because clinical sepsis was rare in this population [16].
Adjusted by multivariate logistic regression for maternal age and the duration of rupture of membranes.