Frequent Genital HSV-2 Shedding among Women during Labor in Soweto, South Africa

Table 3

Deaths known to have occurred among infants during the follow-up period, 𝑛=10.

Maternal age (years)	Maternal comorbidities^a	EGA (weeks)	Birth weight (g)	Delivery route	Maternal HSV-2 serostatus at delivery	Maternal genital HSV-2 (log10 copies/mL)	Days between delivery and swab collection	Age at death (days)	Cause of death
20	HIV (CD4 229) ARVs: 3TC, TDF, NVP	40	3150	Vaginal	Positive	2.28	13	35	Pneumonia
30	HIV (CD4 489) ARV: AZT	39	3130	Vaginal	Positive	2.56	5	36	Possible pneumonia
42	Gestational diabetes	37	2200	Vaginal	Positive	ND	50	Stillborn
33	None	41	3971	Vaginal	Positive	ND	4	Stillborn
22	None	37		Vaginal	Negative^b	ND	0	Stillborn, twin survived
23	None	42	3930	Vaginal	Positive	ND	1	0	Perinatal asphyxia
24	Epilepsy, treated with valproic acid	42	2325	Vaginal	Positive	ND	2	1	Respiratory failure
38	Pregnancy-induced hypertension	41	3230	Vaginal	Negative^b	ND	2	4	Perinatal asphyxia
33	Hypertension	38	2220	Cesarean section	Positive	ND	4	8	Details not available
22	None	37	2780	Cesarean section	Negative^b	ND	1	26	Congenital heart disease, pneumonia

Abbreviations: EGA: estimated gestational age; ARVs: antiretrovirals; 3TC: lamivudine; TDF: tenofovir; NVP: nevirapine; AZT: zidovudine. ND: not detected. ^aAll ten women had a nonreactive rapid plasma reagin (RPR) during the prenatal period. ^bPostpartum HSV Western blot not available.