Table 3: Association between breast milk DNA and HIV-1 RNA load and growth of breastfed HIV-exposed, uninfected infants.

Outcome measure ( )CMV DNA load associations HIV-1 RNA load associations
CrudeAdjustedcCrudeAdjusted

Six-month -scorea (95% CI) (95% CI) (95% CI) (95% CI)

Weight for length−0.05
(−0.40, 0.29)
−0.03
(−0.36, 0.30)
0.30
(−0.03, 0.63)
0.40
(−0.04, 0.83)
Length for age−0.48
(−0.99, −0.08)
−0.52
(−0.93, −0.10)
−0.17
(−0.59, 0.26)
−0.35
(−0.92, 0.21)
Weight for age−0.40
(−0.67, −0.12)
−0.39
(−0.66, −0.13)
0.13
(−0.17, 0.42)
0.11
(−0.26, 0.47)

Change in -scoreb (95% CI) (95% CI) (95% CI) (95% CI)

Weight for length0.63
(−0.05, 1.30)
0.72
(0.04, 1.40)
0.22
(−0.47, 0.91)
−0.62
(−1.50, 0.27)
Length for age−0.04
(−0.56, 0.48)
−0.29
(−0.84, 0.26)
−0.39
(−0.93, 0.15)
0.20
(−0.55, 0.96)
Weight for age0.20
(−0.03, 0.43)
0.16
(−0.05, 0.38)
−0.01
(−0.25, 0.23)
−0.04
(−0.34, 0.26)

aNumbers in the table represent difference in -score at six months of age associated with a one-log10 increase in average breast milk CMV load.
bNumbers in the table represent difference in differences: the change in delta- -score between six months of age and four to six weeks of age associated with a one-log10 increase in average breast milk CMV load.
cAdjusted analysis accounts for infant birth weight and gestational age and maternal HAART use, age, and CD4 count.