Acute infections present during hospital discharges for delivery among pregnant women with multiple gestation compared to women with singleton gestation, Nationwide Inpatient Sample for years 2008–2010 (12,524,118 deliveries).
Condition, (%)
Multiple gestation = 266,751
Singleton gestation = 12,257,367
OR (95% CI)
value
Generalized infections
Sepsis
368 (0.14)
5937 (0.05)
2.85 (2.56, 3.16)
<0.0001
Bacteremia
124 (0.05)
1767 (0.01)
3.23 (2.68, 3.85)
<0.0001
Neurologic
Meningitis
5 (0.002)
74 (0.0006)
3.31 (1.20, 7.25)
0.008
Ear, nose, and throat
Otitis media
106 (0.04)
2040 (0.02)
2.38 (1.96, 2.89)
<0.0001
Pharyngitis
147 (0.05)
3959 (0.03)
1.70 (1.45, 2.01)
<0.0001
Sinusitis
256 (0.10)
5380 (0.04)
2.19 (1.93, 2.48)
<0.0001
Pulmonary
Pneumonia
864 (0.3)
11,026 (0.09)
3.61 (3.37, 3.87)
<0.0001
Influenza
297 (0.10)
3925 (0.03)
3.48 (3.09, 3.91)
<0.0001
Gastrointestinal
Gastrointestinal infectionsa
450 (0.17)
3322 (0.027)
6.23 (5.64, 6.87)
<0.0001
Appendicitis
134 (0.05)
2239 (0.018)
2.76 (2.32, 3.29)
<0.0001
Urologic
Urinary tract infections
5515 (2.1)
85,488 (0.70)
3.01 (2.93, 3.09)
<0.0001
Pyelonephritis
1392 (0.5)
19,280 (0.2)
3.33 (3.15, 3.51)
<0.0001
Skin/dermatology
Cellulitis/abscess skin
907 (0.34)
15,452 (0.13)
2.70 (2.53, 2.89)
<0.0001
MRSA infection (unspec. site)
65 (0.02)
2290 (0.019)
1.31 (1.02, 1.67)
0.031
Composite Infection
10,210 (3.84)
156,613 (1.28)
3.12 (3.05, 3.18)
<0.0001
Cholera, typhoid, salmonella, shigella, amebiasis, and intestinal protozoal diseases.
