Bacterial Load in Daily Urine Samples of Patients Infected with Mycoplasma genitalium, Mutation Analysis, and Response to Treatment

Table 1

Patient number, symptoms, bacterial type, and bacterial load at baseline and on day 4 after treatment with azithromycin 1,5 g. Patients 5 and 11 were excluded from the study. Patient 3 had a negative pretreatment sample but had a titer of 2,36 × 10² copies/mL on day 1. Patient 20 was unable to provide a pretreatment sample due to recent micturition and had a titer of 4,01 × 10⁵ copies/mL on day 1. Patients 13 and 15 had a negative test at day 35 but tested positive at their follow-up appointment a few days later.

Participant number	Symptoms	Bacterial load at baseline, copies/mL	Bacterial load at day 4, copies/mL	Bacterial load at day 35, copies/mL
Wild type
1	—	1,30 × 10^3	—	—
2	—	1,86 × 10^4	—	—
4	—	4,80 × 10^2	—	—
7	—	4,96 × 10^1	—	—
12	—	3,18 × 10^2	—	—
14	—	5,97 × 10^3	—	—
18	—	1,20 × 10^3	—	—
19	—	6,97 × 10^2	—	—
A2058G mutation
3	—	—	4,31 × 10^2	3,09 × 10^2
9	Symptomatic	1,13 × 10^3	6,64 × 10^2	7,56 × 10^2
17	Symptomatic	1,91 × 10^4	8,66 × 10^3	4,08 × 10^3
21	—	1,40 × 10^5	7,28 × 10^5	2,56 × 10^3
A2059G mutation
6	—	4,70 × 10^2	2,51 × 10^3	4,08 × 10^2
8	—	3,47 × 10^2	9,92 × 10^3	2,37 × 10^2
10	—	5,18 × 10^3	2,03 × 10^3	1,16 × 10^4
13	Symptomatic	1,30 × 10^3	1,33 × 10^2	—
15	Symptomatic	1,35 × 10^4	2,95 × 10^3	—
16	—	3,79 × 10^3	3,76 × 10^3	—
20	—	Not tested on day 0	1,92 × 10^5	7,06 × 10^2