Infectious Diseases in Obstetrics and Gynecology / 2016 / Article / Tab 1

Review Article

Prevalence of Chlamydia trachomatis among Childbearing Age Women in India: A Systematic Review

Table 1

Characteristics of the studies addressing Chlamydia trachomatis (CT) prevalence among childbearing age women in India.

AuthorYearSettingLocationPopulationAgeDiagnostic methodSample sourcePrevalence (95% CI)1Validity

Vidwan et al. [15]2012ANC clinicTamil NaduPregnant (≥28 weeks’ gestation)784Mean: 25.8
Range: 18–39
NAAEndocervical0.1% (0–0.38%)This is the largest study on CT prevalence among healthy pregnant mothers in South India. But project sample population may not represent local delivering female population.

Patel et al. [16]2010GYN clinicNew DelhiSymptomatic, nonpregnant335Median: 29
Range: 18–60
PCREndocervical23.0%Used in-house PCR method which was cost-effective; included only symptomatic patients.

Becker et al. [17]2010GYN clinicsKarnatakaSymptomatic335Mean: 30.7PCREndocervical2.7% It has good sample size;women were recruited from gynecology clinics; itmay lead to enrollment of low risk women.

Dwibedi et al. [18]2009OB/GYN clinicOrissaSymptomatic71 Mean: 31.5
(SD: 7.3)
PCREndocervical7.0% It has small sample size. It is the first report from the region. It may help clinicians of the region in treating cases with similar symptoms.

Singh et al. [19]2003GYN clinicNew DelhiSymptomatic and asymptomatic28018–25
25–35
35–452
PCREndocervical28.5%
7.6%
3.2%
Studied age-wise prevalence rate and determined most prevalent serovars of CT.

Joyce et al. [20]2004Community3Tamil NaduSymptomatic and asymptomatic1066Range: 15–45PCR
ELISA
Urine
Blood
1.1% (0.5–1.7%)
3.3% (1.9–4.7%)
It is the first population based study in India. It has the largest sample size. It used two methods to determine prevalence.

95% CI reported when available from paper.
2Reported only as age groups; no measure of central tendency available.
95% CI: 95% confidence interval; ANC: antenatal care; OB/GYN: obstetrics and gynecology; GYN: gynecology; SD: standard deviation; NAA: nucleic acid amplification; PCR: polymerase chain reaction; ELISA: enzyme-linked immunosorbent assay; DFA: direct fluorescent antibody; STI: sexually transmitted infection.
3Representative sample taken from 3 randomly selected districts by using the probable proportional to size cluster survey method.

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