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Infectious Diseases in Obstetrics and Gynecology
Volume 2019, Article ID 2613962, 7 pages
Research Article

Challenges in the Contemporary Management of Syphilis among Pregnant Women in New Orleans, LA

1Baylor College of Medicine/Texas Children’s Hospital, Department of Obstetrics and Gynecology, Houston, TX, USA
2Louisiana State University Health Sciences Center, Department of Obstetrics and Gynecology, New Orleans, LA, USA
3Baylor College of Medicine/Texas Children’s Hospital, Institute for Clinical and Translational Research, USA
4Baylor College of Medicine/Texas Children’s Hospital, Section of Neonatology, Houston, TX, USA
5Baylor College of Medicine/Texas Children’s Hospital, Department of Obstetrics and Gynecology, San Antonio, TX, USA

Correspondence should be addressed to Irene A. Stafford; ude.mcb@droffats.eneri

Received 21 November 2018; Accepted 28 January 2019; Published 13 February 2019

Academic Editor: Diane M. Harper

Copyright © 2019 Irene A. Stafford et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The aim of this retrospective review is to evaluate trends in the management of maternal and congenital syphilis (CS) in a tertiary care center in New Orleans, LA. Study Design. All cases of maternal and neonatal syphilis over a five year period at Touro Infirmary, New Orleans, LA, were identified using ICD-9/10 codes. Charts were reviewed for demographic and obstetrical variables, stage of syphilis at diagnosis, lab values, and treatment regimen. Newborn treatment and other outcomes were recorded. Results. During the study period 106 infected mother-baby pairs were identified. Of these, 73 charts are available for review. 41% (n = 30) of women received inadequate therapy according to their stage of disease. 9% of newborns (n = 6) were found to be symptomatic for CS; however, only 83.3% of these were admitted to the neonatal intensive care unit. Only 20% (n = 6) of infants were adequately treated with an extended penicillin regimen if the mother was not adequately treated. Furthermore, only 63.0% of newborns had a nontreponemal titer performed. Conclusion. With rising rates of CS, strict adherence to the 2015 CDC guidelines for treatment of syphilis must be maintained.