Total and Free 25-Hydroxy-Vitamin D and Bacterial Vaginosis in Pregnant African American Women

Table 5

Multinomial odds of Nugent score category (intermediate flora and bv relative to normal flora) by total and free 25(oh)d concentration.

Vitamin D Measure (ng/mL)	Nugent Score Category
	Intermediate Flora		BV
	Coefficient	aOR (95 CI)	Coefficient	aOR (95 CI)
Visit 1^1
Total 25(OH)D	-0.04	0.96 (0.89. 1.03)	-0.04	0.96 (0.91, 1.01)
Free 25(OH)D	0.10	1.11 (0.78, 1.58)	0.06	1.06 (0.80, 1.41)
Visit 2^1
Total 25(OH)D	-0.03	0.97 (0.92, 1.02)	-0.06	0.94 (0.89, 0.99)
Free 25(OH)D	-0.18	0.84 (0.63, 1.11)	-0.13	0.88 (0.69, 1.10)
Visit 2-Visit 1^2
Δ Total 25(OH)D	-0.11	0.90 (0.83, 0.97)	-0.15	0.86 (0.78, 0.95)
Δ Free 25(OH)D	-0.31	1.1 (0.78, 1.56)	-0.47	0.62 (0.41, 0.95)

Bold, italic font, indicates a significant difference for women according to Nugent score category at α = 0.05.
¹Model adjusts for maternal age, parity, insurance status (Medicaid, private), first prenatal BMI, gestational age of visit, and receipt of antibiotics in the month prior to the visit.
²Model adjusts for maternal age, parity, insurance status (Medicaid, private), and first prenatal BMI; baseline 25(OH)D concentration, Nugent score, and gestational age of visit, in addition to number of weeks between visits and receipt of antibiotics between visits.