Research Article

Azithromycin in the Treatment of Preterm Prelabor Rupture of Membranes Demonstrates a Lower Risk of Chorioamnionitis and Postpartum Endometritis with an Equivalent Latency Period Compared with Erythromycin Antibiotic Regimens

Table 1

Maternal demographics.

CharacteristicAzithromycin group
Erythromycin group

Maternal age (years) (20-43) (18-47)
Advanced maternal age49 (35)45 (27)0.104δ
Gestational age at diagnosis (25-33) (26-33)0.380
Nulliparous108 (76.1)110 (65.5)0.042δ
BMI (kg/m2) (21-48.9) (20.8-43.9)0.282
Pregestational diabetes15 (10.6)20 (11.9)0.153δ
Group β-streptococcus positive28 (19.7)38 (22.6)0.534δ
Hypertensive disorders in pregnancy29 (20.4)41 (24.4)0.403δ
Race
 White60 (42.3)74 (44)0.832δ
 Asian30 (21.1)31 (18.5)0.555δ
 Hispanic37 (26.7)51 (30.4)0.486δ
 Black14 (9.9)13 (7.1)0.509δ

Data are presented as deviation (range) or n (%). δStatistics performed using test. Statistics performed using Welch two-sample -test.