Azithromycin in the Treatment of Preterm Prelabor Rupture of Membranes Demonstrates a Lower Risk of Chorioamnionitis and Postpartum Endometritis with an Equivalent Latency Period Compared with Erythromycin Antibiotic Regimens

Table 2

Pregnancy and neonatal outcomes.

Characteristic	Azithromycin group	Erythromycin group
Clinical chorioamnionitis	19 (13.4)	42 (25)	0.010
Histological chorioamnionitis	99 (69.7)	109 (64.9)	0.367
Latency interval	5 (6-11)	4.75 (6 – 10.8)	0.836
Cesarean delivery	76 (50.7)	83 (49.4)	0.470
Meconium-stained amniotic fluid	38 (26.8)	26 (15.5)	0.014
Postpartum endometritis	21 (14.8)	52 (31)	<0.001
Neonatal sepsis	7 (4.9)	25 (14.9)	0.004

Data are presented as median (interquartile range) or (%). ^δStatistics performed using test. Statistics performed using the Wilcoxon rank-sum test.