Phase I Study in Healthy Women of a Novel Antimycotic Vaginal Ovule Combining Econazole and Benzydamine

Table 2

Mean (±SD) (ng/mL × h) of plasma econazole measured and calculated on Days 1 and 3 of treatment with T and R1 and of plasma benzydamine and benzydamine N-oxide measured and calculated on Days 1 and 3 of treatment with T and R2.

Analyte	Day 1		Day 3
	T	R1	T	R1
Econazole
	T	R2	T	R2
Benzydamine
Benzydamine N-oxide

: area under the concentration curve from administration to the last observed concentration time ; T: test fixed-dose of econazole nitrate 150 mg/benzydamine hydrochloride 6 mg vaginal ovules; R1: reference 1 econazole nitrate 150 mg only ovules; R2: reference 2 benzydamine hydrochloride 6 mg only ovules.