Research Article
Documented β-Lactam Allergy and Risk for Cesarean Surgical Site Infection
Table 3
Unadjusted and adjusted association between maternal and obstetric characteristics, including β-lactam allergy and surgical site infection.
| Covariate | OR for SSI | value | aOR for SSI | value |
| β-Lactam allergy | 2.13 (1.50-3.02) | <0.001 | 1.97 (1.24–3.14) | 0.004 | Age | 0.97 (0.95-0.99) | 0.004 | 0.98 (0.96–1.00) | 0.104 | Race | | | | | White | Ref | | Ref | | African American | 1.36 (1.02-1.80) | 0.033 | 1.26 (0.82–1.93) | 0.290 | Asian | 1.05 (0.59-1.85) | 0.865 | 1.49 (0.79–2.82) | 0.217 | Other | 1.20 (0.53-2.74) | 0.678 | 1.80 (0.77–4.22) | 0.173 | Multiracial | 2.25 (0.70-7.21) | 0.174 | 2.40 (0.69–8.37) | 0.170 | Ethnicity | | | | | Non-Hispanic | Ref | | Ref | | Hispanic | 1.00 (0.79–1.27) | 0.987 | 0.98 (0.66–1.47) | 0.934 | Insurance | | | | | Private | Ref | | Ref | | Public | 1.32 (1.02–1.72) | 0.036 | 1.25 (0.87–1.79) | 0.217 | None/other/unknown | 0.76 (0.37–1.58) | 0.462 | 0.78 (0.34–1.77) | 0.559 | Delivery BMI | 1.04 (1.02-1.05) | <0.001 | 1.02 (1.00–1.04) | 0.014 | Smoking during pregnancy | 0.71 (0.26–1.91) | 0.496 | 0.48 (0.15–1.545) | 0.221 | Chorioamnionitis | 2.84 (2.03-3.98) | <0.001 | 1.52 (0.98–2.35) | 0.060 | Duration of membrane rupture (min) | 1.00 (0.99–1.00) | 0.739 | 1.00 (0.99–1.00) | 0.736 | Preterm birth | 1.67 (1.27–2.20) | <0.001 | 1.47 (1.06–2.05) | 0.021 | Cesarean indication | | | | | Scheduled | Ref | | Ref | | Unscheduled—fetal well-being related | 1.89 (1.36-2.64) | <0.001 | 1.65 (1.13–2.41) | 0.010 | Unscheduled—labor related | 4.64 (3.28-6.56) | <0.001 | 3.60 (2.39–5.42) | <0.001 | Other | 2.04 (1.49–2.80) | <0.001 | 1.93 (1.35–2.77) | <0.001 | Pregestational diabetes | 1.43 (0.87–2.35) | 0.158 | 1.18 (0.68–2.03) | 0.557 | Gestational diabetes | 1.15 (0.80–1.65) | 0.441 | 1.01 (0.67–1.52) | 0.960 | Hypertension | 2.17 (1.69–2.77) | <0.001 | 1.63 (1.21–2.18) | 0.001 | Group B Streptococcus colonization | 0.70 (0.51–0.96) | 0.030 | 0.69 (0.49–0.98) | 0.039 | β-Lactam received | 0.77 (0.58–1.01) | 0.060 | 0.95 (0.68–1.33) | 0.778 | Non-β-lactam received | 2.46 (1.90–3.18) | <0.001 | 1.43 (1.01–2.02) | 0.045 |
|
|