New Sensitive Kinetic Spectrophotometric Methods for Determination of Omeprazole in Dosage Forms

Table 4

Analytical parameters for the proposed fixed time methods for determination of OMZ.

Method	Time	Range	𝑅	Slope	Intercept	LOD	LOQ
	(min)	(𝜇gmL^−1)		(b) ± SD	(a) ± SD	(𝜇gmL^−1)	(𝜇gmL^−1)
Iodine	5	1.50–12.00	0.9915	0.0751 ±0.0049	0.0226 ±0.0095	0.42	1.27
	15	0.50–6.00	0.9955	0.1589 ±0.0017	0.0060 ±0.0073	0.15	0.46
	25	0.40–5.00	0.9992	0.2198 ±0.0044	0.0064 ±0.0085	0.13	0.39
	35	0.30–4.00	0.9995	0.2649 ±0.0042	0.0323 ±0.0061	0.08	0.23
	45	0.10–3.00	0.9990	0.3069 ±0.0067	0.0693 ±0.0032	0.03	0.10
DDQ	1	10.00–120.00	0.9982	0.0065 ±0.0002	0.0013 ±0.0065	3.28	9.94
	2	5.00–60.00	0.9992	0.0155 ±0.0001	0.0097 ±0.0028	0.59	1.80
	3	3.00–40.00	0.9993	0.0249 ±0.0006	0.0246 ±0.0036	0.48	1.45
	4	2.50–30.00	0.9992	0.0320 ±0.0007	0.0305 ±0.0017	0.18	0.53
	5	0.60–25.00	0.9998	0.0366 ±0.0004	0.0299 ±0.0021	0.19	0.57