Research Article
New Sensitive Kinetic Spectrophotometric Methods for Determination of Omeprazole in Dosage Forms
Table 4
Analytical parameters for the proposed fixed time methods for determination of OMZ.
| Method | Time | Range | | Slope | Intercept | LOD | LOQ | (min) | () | (b) ± SD | (a) ± SD | () | () |
| Iodine | 5 | 1.50–12.00 | 0.9915 | 0.0751 ±0.0049 | 0.0226 ±0.0095 | 0.42 | 1.27 | 15 | 0.50–6.00 | 0.9955 | 0.1589 ±0.0017 | 0.0060 ±0.0073 | 0.15 | 0.46 | 25 | 0.40–5.00 | 0.9992 | 0.2198 ±0.0044 | 0.0064 ±0.0085 | 0.13 | 0.39 | 35 | 0.30–4.00 | 0.9995 | 0.2649 ±0.0042 | 0.0323 ±0.0061 | 0.08 | 0.23 | 45 | 0.10–3.00 | 0.9990 | 0.3069 ±0.0067 | 0.0693 ±0.0032 | 0.03 | 0.10 |
| DDQ | 1 | 10.00–120.00 | 0.9982 | 0.0065 ±0.0002 | 0.0013 ±0.0065 | 3.28 | 9.94 | 2 | 5.00–60.00 | 0.9992 | 0.0155 ±0.0001 | 0.0097 ±0.0028 | 0.59 | 1.80 | 3 | 3.00–40.00 | 0.9993 | 0.0249 ±0.0006 | 0.0246 ±0.0036 | 0.48 | 1.45 | 4 | 2.50–30.00 | 0.9992 | 0.0320 ±0.0007 | 0.0305 ±0.0017 | 0.18 | 0.53 | 5 | 0.60–25.00 | 0.9998 | 0.0366 ±0.0004 | 0.0299 ±0.0021 | 0.19 | 0.57 |
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