New Sensitive Kinetic Spectrophotometric Methods for Determination of Omeprazole in Dosage Forms

Table 6

Determination of OMZ in presence of common excipients by the proposed fixed time methods.

Ingredient	Recovery ( % ± SD)^a
	Iodine method	DDQ method
Starch (50)^b	99.26 ±0.39	98.86 ±0.66
Glucose (10)	99.42 ±1.02	99.33 ±1.53
Lactose (10)	100.49 ±1.35	101.11 ±1.45
Acacia (10)	101.02 ±0.75	100.85 ±0.64
MS^c (10)	99.31 ±0.96	98.94 ±0.75
Average ± SD	99.90 ±0.80	99.82 ±1.08
Pool SD	0.89	1.01

a Values are mean of three determinations.
b Figures in parenthesis are the amounts in mg added per 20 mg of OMZ.
c MS = Magnesium stearate.