Research Article

A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance

Figure 8

(a) MS/MS analysis (with accurate mass determination) of the protonated ion of MS447. (b) Schematic of the MS/MS fragmentation interpretation of MS447.
768743.fig.008a
(a)
768743.fig.008b
(b)