Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate

Table 3

The precision of the proposed methods at three concentration levels of AMD.

Method	Nominal concentration (𝜇g mL^−1)	RSD%^(a)
Spectrophotometric	8.0	0.96
	40.0	0.83
	60.0	0.87
Spectrofluorometric	0.1	1.01
	4.0	0.58
	8.0	0.46

^(a)Values are mean of five determinations.