Fluorescence Spectrometric Determination of Drugs Containing 𝜶-Methylene Sulfone/Sulfonamide Functional Groups Using N¹-Methylnicotinamide Chloride as a Fluorogenic Agent

Table 3

Regression analysis parameters for the determination of 1–4 in spiked human plasma samples using the proposed method.

Drug	Linearity range	Slope		Intercept		𝑅^2
		Mean	SE	Mean	SE
1	5–150 μg/mL	4.8849	0.100	118.53	1.55	0.9991
2	10–1000 ng/mL	0.7930	0.020	192.15	1.70	0.999
3	10–1700 ng/mL	0.5342	0.010	49.64	1.57	0.9989
4	30–2350 ng/mL	0.3110	0.003	254.48	1.35	0.9995

Average of triplicate analyses, 13 data points.