Low-Level Detection of Poly(amidoamine) PAMAM Dendrimers Using Immunoimaging Scanning Probe Microscopy

Figure 1

Schematic of capture assay platform: (a) immobilize avidin onto Au substrate with controlled surface area using DSP and (b) expose substrate to biotinylated PAMAM dendrimers. (c) The captured biotinylated PAMAM dendrimers can be fluorescently labeled for additional verification of immobilization and patterning of dendrimers.