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International Journal of Analytical Chemistry
Volume 2012 (2012), Article ID 918292, 7 pages
Research Article

Determination of Total Selenium in Infant Formulas: Comparison of the Performance of FIA and MCFA Flow Systems

Department of Analytical Chemistry, School of Chemistry, Universidad de la República (UdelaR), Avenue Gral. Flores 2124, 11800 Montevideo, Uruguay

Received 30 September 2011; Revised 8 December 2011; Accepted 8 December 2011

Academic Editor: Hian Kee Lee

Copyright © 2012 Mariela Pistón and Moisés Knochen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Two flow methods, based, respectively, on flow-injection analysis (FIA) and on multicommutated flow analysis (MCFA), were compared with regard to their use for the determination of total selenium in infant formulas by hydride-generation atomic absorption spectrometry. The method based on multicommutation provided lower detection and quantification limits (0.08 and 0.27 μg L−1 compared to 0.59 and 1.95 μ L−1, resp.), higher sampling frequency (160 versus. 70 samples per hour), and reduced reagent consumption. Linearity, precision, and accuracy were similar for the two methods compared. It was concluded that, while both methods proved to be appropriate for the purpose, the MCFA-based method exhibited a better performance.