Two Validated Spectrofluorometric Methods for Determination of Gemifloxacin Mesylate in Tablets and Human Plasma

Table 2

Intraday and interday precision of the proposed methods.

Method	Conc.; (ng/mL)	Recovery (%) ± SD^a	Intraday precision		Interday precision
			Mean ± SD^a	%RSD	Mean ± SD^a	%RSD
	20	99.86±1.17	100.63±1.13	1.18	99.10±1.50	1.51
Micelle-enhanced; spectrofluorometric	125	96.49±0.40	99.82±0.82	0.82	99.63±1.85	1.86
	500	99.76±1.66	100.34±1.09	1.08	100.23±1.43	1.42
	250	99.24±2.25	99.31±0.58	0.58	98.36±1.89	1.90
Hantzsch reaction	500	100.71±1.98	100.56±0.70	0.70	100.71±1.44	1.43
	1000	99.35±1.44	99.86±0.44	0.44	99.57±0.82	0.82

aMean of six determinations.