Titrimetric and Spectrophotometric Methods for the Assay of Ketotifen Using Cerium(IV) and Two Reagents

Table 5

Results of analysis of tablets by the proposed methods and statistical comparison with the reference method.

Tablets analysed	Label claim, mg/tablet	Found* (percent of label claim ± SD)
		Reference method	Proposed methods
			Method A	Method B	Method C
Asthafen	1	100.8 ± 0.91	101.4 ± 0.89	102.8 ± 1.91	102.1 ± 1.75
			𝑡=1.05	𝑡=2.11	𝑡=2.16
			𝐹=1.05	𝐹=4.41	𝐹=3.7
Ketasma	1	102.3 ± 1.02	100.6 ± 0.98	102.8 ± 1.36	101.3 ± 0.88
			𝑡=2.69	𝑡=0.66	𝑡=1.66
			𝐹=1.08	𝐹=1.78	𝐹=1.34

 ∗Mean value of five determinations;
Tabulated 𝑡 value at the 95% confidence level is 2.78.
Tabulated 𝐹 value at the 95% confidence level is 6.39.