Utilization of N-Bromosuccinimide as a Brominating Agent for the Determination of Sumatriptan Succinate in Bulk Drug and Tablets

Table 3

Evaluation of intra-day and inter-day precision and accuracy.

Method	STS* taken	Intra-day (𝑛=5)			Inter-day (𝑛=5)
		STS found^a	%RSD^b	%RE^c	STS found^a	%RSD^b	%RE^c
A; (Titrimetry)	4.00	3.98	0.90	0.55	3.95	1.39	1.21
	6.00	5.99	0.92	0.23	6.04	1.09	0.65
	8.00	8.05	0.73	0.59	8.06	1.06	0.76
B; (Spectrophotometry)	6.00	6.06	0.97	0.96	6.08	1.83	1.42
	9.00	9.10	1.04	1.06	9.12	1.57	1.32
	12.0	11.9	1.02	0.94	11.9	1.40	1.12
C; (Spectrophotometry)	1.00	1.02	1.44	1.55	1.02	2.20	1.93
	2.00	1.98	0.94	1.14	1.97	1.37	1.40
	3.00	2.97	0.63	0.85	2.97	0.91	1.02

∗In method A, STS taken/found are in mg and they are μg mL⁻¹ in methods B and C.
^aMean value of five determinations.
^bRelative standard deviation (%).
^cRelative error (%).