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International Journal of Analytical Chemistry
Volume 2014, Article ID 239641, 5 pages
Research Article

Identification of New Metabolites of Bacterial Transformation of Indole by Gas Chromatography-Mass Spectrometry and High Performance Liquid Chromatography

School of Biotechnology, Yeungnam University, Gyeongsan 712-749, Republic of Korea

Received 22 September 2014; Revised 9 November 2014; Accepted 21 November 2014; Published 4 December 2014

Academic Editor: Jane Thomas-Oates

Copyright © 2014 Pankaj Kumar Arora and Hanhong Bae. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Arthrobacter sp. SPG transformed indole completely in the presence of an additional carbon source. High performance liquid chromatography and gas chromatography-mass spectrometry detected indole-3-acetic acid, indole-3-glyoxylic acid, and indole-3-aldehyde as biotransformation products. This is the first report of the formation of indole-3-acetic acid, indole-3-glyoxylic acid, and indole-3-aldehyde from indole by any bacterium.