Multianalytical Method Validation for Qualitative and Quantitative Analysis of Solvents of Abuse in Oral Fluid by HS-GC/MS

Table 4

Intra- and interday accuracy and precision by GC/MS.

	QC sample ()	Intraday		Interday
		Accuracy (%)	RSD (%)	Accuracy (%)	RSD (%)
Ethanol	LLOQ	3.4	10.2	6.7	5.0
	LQC	7.4		3.0
	MQC	5.5		5.3
	HQC	9.2		6.1	2.5
	DQC	8.6		11.6	0.4
Diethyl ether	LLOQ	7.3		7.4
	LQC	5.1		8.1
	MQC	9.2		11.9
	HQC	13.0		7.0	2.6
	DQC	13.6	0.1	5.0	0.6
Dichloromethane	LLOQ	8.9		11.1
	LQC	10.7	4.9	13.7
	MQC	7.2		10.7
	HQC	12.2		9.7
	DQC	13.1		6.1
Chloroform	LLOQ	7.9		7.4
	LQC	9.6		4.0
	MQC	10.6		8.2
	HQC	13.8		6.5
	DQC	13.5		2.3
Ethyl acetate	LLOQ	8.3		14.1	6.6
	LQC	5.3		5.0	0.4
	MQC	7.7		4.8
	HQC	5.9		9.7
	DQC	4.9		3.9
n-Butanol	LLOQ	3.3	4.9	7.7	10.0
	LQC	5.7		2.9
	MQC	5.0		3.7
	HQC	8.8		0.4
	DQC	0.9		6.8

RSD: relative standard deviation, LQC: low quality control, MQC: middle quality control, HQC: high quality control, and DQC: dilution quality control.