Enantioseparation of Citalopram by RP-HPLC, Using Sulfobutyl Ether-β-Cyclodextrin as a Chiral Mobile Phase Additive

Figure 3

Effect of the pH of aqueous buffer. Mobile phase: aqueous buffer/methanol/acetonitrile of 21 : 3 : 1 (v/v/v); 5 mM sodium dihydrogen phosphate, 12 mM SBE-β-CD, flow rate of 1.0 mL/min, detection wavelength of 240 nm, and temperature of 25°C. and , retention factors of ()-CIT and ()-CIT, respectively; , resolution.