Research Article
Enantioseparation of Citalopram by RP-HPLC, Using Sulfobutyl Ether-β-Cyclodextrin as a Chiral Mobile Phase Additive
Table 1
Effect of the concentration of SBE-β-CD in aqueous phase.
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Mobile phase: aqueous buffer/methanol/acetonitrile of 21 : 3 : 1 (v/v/v), concentration of SBE-β-CD in aqueous buffer of 4, 8, 12, and 16 mM, 5 mM sodium dihydrogen phosphate, pH of 2.5, flow rate of 1.0 mL/min, detection wavelength of 240 nm, temperature of 25°C, and , and retention factors of ()-CIT and ()-CIT, respectively; , resolution, and , separation factor. |