Isocratic Resolution of Fluoroquinolone-Based Antibiotics on the Phenylethyl-Bonded Phase under Nonaqueous Elution: A Consideration of the Separation Mechanism

Figure 2

Resolution of ofloxacin and ciprofloxacin under the elution of ACN/1/3 by volume (acetonitrile/acetic acid/triethylamine, ) on the C₈ (a) and phenylethyl (b) stationary phases. Note that the elution order has been reversed. The numbering system is the same as that in Figure 1.

(a)

(b)