Determination of Chlorpromazine, Haloperidol, Levomepromazine, Olanzapine, Risperidone, and Sulpiride in Human Plasma by Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

Table 2

Optimal compound related settings.

Antipsychotics	Q1 (m/z)	Q3 (m/z)	DP (v)	EP (v)	CE (v)	CXP (v)
Chlorpromazine	319.1	86.1	65	10	32	4
	319.1	214.1	60	15	30	3
	319.1	246.1	57	10	25	4
Haloperidol	376.1	123.0	55	15	55	4
	376.1	165.2	60	10	35	3
	376.1	358.2	47	10	35	2
Levomepromazine	329.2	58.0	50	10	45	2
	329.2	100.1	70	15	38	3
	329.2	210.2	50	15	30	4
Olanzapine	313.2	198.2	45	20	30	3
	313.2	256.0	62	15	35	2
	313.2	169.1	53	20	40	2
Risperidone	411.2	191.2	80	20	40	3
	411.2	110.1	55	20	30	2
	411.2	82.2	54	10	38	3
Sulpiride	342.2	112.1	72	15	35	5
	342.2	214.1	45	15	45	3
	342.2	98.1	43	10	45	2
Repaglinide	453.3	230.2	32	10	43	3
	453.3	174.2	35	15	45	3