Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

Table 7

Robustness test using the experimental model of Plackett-Burman.

Analytical Parameter	Factorial Combination
	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
A	1	1	1	0	1	0	0	0	-1	-1	-1	0	-1	0	0
B	0	1	1	1	0	1	0	0	0	-1	-1	-1	0	-1	0
C	0	0	1	1	1	0	1	0	0	0	-1	-1	-1	0	-1
D	1	0	0	1	1	1	0	0	-1	0	0	-1	-1	-1	0
E	0	1	0	0	1	1	1	0	0	-1	0	0	-1	-1	-1
F	1	0	1	0	0	1	1	0	-1	0	-1	0	0	-1	-1
G	1	1	0	1	0	0	1	0	-1	-1	0	-1	0	0	-1

A–G: selected factors; 1–15: N (number of experiments) = 2n + 1, where n = number of factors; −1, 0, +1: levels for the factors.