Optimization of Resolving Power, Fragmentation, and Mass Calibration in an Orbitrap Spectrometer for Analysis of 24 Pesticide Metabolites in Urine

Table 4

Number of ions (diagnostic and fragment ions) into the six mass accuracy ranges considered at 10,000, 25,000, and 50,000 FWHM.

Resolving Power	∆m (ppm)
	≤ 1	1 – 2	2 – 3	3 – 4	4 – 5	> 5
10,000	2	12	19	9	0	2
25,000	1	22	19	2	0	0
50,000	0	30	11	3	0	0

Acquisition conditions: ESI+/ESI- in separated injections, HCD fragmentation 20 eV, and external mass calibration.