Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

<div>Mean plasma concentration-time curve of (a) PMZ and (b) PMZSO in rat plasma samples after oral administration of PMZ with or without <i>S. chinensis</i> (<i>n</i> = 6-7). Data were analyzed by one-way ANOVA. All data are presented as mean ± SD.</div>

International Journal of Analytical Chemistry

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Figure 4

Figure 4: Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study 

Figure 4 | Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study 