Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

<div>Mean plasma concentration-time curve of schisandrin after oral administration of the <i>S. chinensis</i> water extract once or for continuously three weeks, coadministered with or without PMZ (<i>n</i> = 6–7). Data were analyzed by one-way ANOVA. All data are presented as mean ± SD.</div>

International Journal of Analytical Chemistry

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Figure 5

Figure 5: Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study 

Figure 5 | Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study 