Research Article

Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC-MS/MS and Its Application to a Pharmacokinetic Study

Table 2

Regression equations, linear ranges, and LLOQs of the three compounds.

CompoundRegression equationR2Linear range (ng/mL)Limit of quantification (ng/mL)

PromethazineY = 0.016464X + 0.0011500.99830.5–2000.5
Promethazine sulfoxideY = 0.041898X + 0.0011870.99610.5–2000.5
SchisandrinY = 0.054003X + 0.0014370.99860.5–2000.5