Stability of Propofol (2,6-Diisopropylphenol) in Thermal Desorption Tubes during Air Transport

Table 1

Given and measured propofol amounts of Tenax sorbent tubes. The column “target” shows the desired concentration per tube. The column “weighed” shows the calculated amounts of propofol per tube and “measured” shows the actual measured amount. The columns measured-weighed and Δmeasured-reference displays the percentual difference of the columns, with reference to the measured mass.

liquid
	reference			samples stored at 4°C			samples stored at 22°C			mailed samples
target	weighed	measured	Δmeasured- weighed	weighed	measured	Δmeasured-weighed	weighed	measured	Δmeasured-weighed	weighed	measured	Δmeasured-weighed
ng	ng	ng	%	ng	ng	%	ng	ng	%	ng	ng	%
10	9.8	8.6	-14.0	8.6	8.3	-3.6	9.6	9.6	0.0	9.5	9.7	2.1
20	18.5	17.3	-6.9	15.5	15.7	1.3	18.2	17.2	-5.8	18.1	16.2	-11.7
50	47.8	44.3	-7.9	38.3	40.4	5.2	45.5	43.1	-5.6	46.5	35.2	-32.1
100	96.4	92.5	-4.2	85.6	87.2	1.8	95.4	91.7	-4.0	95.4	81.6	-16.9
mean			-8.3			1.2			-3.9			-14.7
gaseous
	reference			samples stored at 4°C			samples stored at 22°C			mailed samples
target	measured			measured		Δmeasured- reference	measured		Δmeasured- reference	measured		Δmeasured- reference
ng	ng			ng		%	ng		%	ng		%
20	22.6			29.6		31.0	18.6		-17.7	26.5		17.3
40	45.3			54.1		19.4	37.2		-17.9	48.0		6.0
60	65.3			87.6		34.2	66.1		1.2	68.8		4.1
80	81.0			122.0		50.6	76.2		-5.9	106.0		30.9
100	114.3			157.7		38.0	115.2		0.8	112.3		-1.7
						34.6			-7.9			11.3